Founder Eric Tan attributes recognition to decades of technical expertise, diagnostic accuracy and customer-first service

SINGAPORE, Sept. 14, 2026 /PRNewswire/ — Doctor Cars Pte Ltd, a leading automotive repair and servicing specialist in Singapore, has been recognised with a Distinguished Brand Award, underscoring the company’s longstanding commitment to technical excellence, customer satisfaction and professional automotive care.

Doctor Cars has built its reputation by focusing on accurate diagnostics, quality workmanship and long-term customer relationships. Over the years, the company has grown by helping motorists address complex vehicle issues through a diagnostic-first approach that prioritises identifying root causes rather than simply treating symptoms.

For Founder Eric Tan, the company’s success has always been rooted in a commitment to technical excellence and customer care.

“From the beginning, our goal has been to provide motorists with reliable solutions they can trust,” said Tan.

“We believe every customer deserves honest advice, accurate assessments and quality repairs. By focusing on doing the job right and continuously improving our technical capabilities, we have been able to build lasting relationships with our customers and support them throughout their vehicle ownership journey.”

The Distinguished Brand Award reflects the company’s ongoing efforts to uphold these standards while adapting to the evolving needs of modern vehicle owners.

Building a Reputation Through Technical Excellence

Operating in an industry where trust and technical competence are essential, Doctor Cars has built its reputation by focusing on accurate diagnostics and long-term repair solutions rather than short-term fixes.

The company specialises in engine repairs, gearbox servicing, radiator solutions and comprehensive vehicle maintenance, serving motorists across Singapore with a diagnostic-first approach designed to identify the root causes of vehicle issues.

According to Tan, modern vehicles have become increasingly sophisticated, requiring workshops to continuously upgrade their technical capabilities and diagnostic expertise.

“Today’s vehicles are far more complex than they were a decade ago,” he said. “Successful servicing is no longer just about repairing a fault. It requires understanding increasingly advanced systems and accurately diagnosing problems before recommending solutions.”

This commitment to technical accuracy has become one of the key pillars behind Doctor Cars’ growth and reputation within the automotive servicing sector.

Customer Trust at the Core

While technical expertise remains critical, Tan believes customer trust has been equally important in the company’s success.

The workshop has built a loyal customer base through transparent communication, practical recommendations and consistent service quality.

“Our customers rely on us to help them make informed decisions about their vehicles,” said Tan.

“That responsibility is something we take seriously. We believe trust is earned through consistency, honesty and delivering results.”

Over the years, much of Doctor Cars’ growth has been driven by customer referrals and repeat business, reflecting the confidence motorists place in the company’s services.

Investing in the Future of Automotive Servicing

Following the Distinguished Brand Award recognition, Doctor Cars intends to continue strengthening its technical capabilities, investing in diagnostic technologies and enhancing workforce development to meet evolving industry demands.

As vehicle technology continues to advance, the company sees continuous learning and innovation as critical to maintaining service excellence.

“The automotive industry is constantly evolving,” said Tan. “Receiving this award is an achievement we are proud of, but it also motivates us to continue improving. Our goal is to remain a trusted partner for motorists by delivering reliable expertise and quality workmanship for years to come.”

A Milestone That Reflects Years of Dedication

For Tan, the award is ultimately a reflection of the collective efforts of his team and the loyalty of customers who have supported the business throughout its journey.

“Recognition is meaningful because it acknowledges the hard work that happens behind the scenes every day,” he said. “We are grateful for the trust our customers have placed in us and remain committed to delivering the standards that earned this recognition.”

About Doctor Cars

Doctor Cars Pte Ltd is a Singapore-based automotive repair and servicing specialist providing engine repairs, gearbox servicing, radiator solutions, air-conditioning maintenance and comprehensive vehicle care services. Guided by a diagnostic-first philosophy and a commitment to quality workmanship, the company continues to help motorists maintain vehicle reliability, safety and performance through expert automotive solutions.

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SOURCE Doctor Cars Pte Ltd

CYBERJAYA, Malaysia, Sept. 14, 2026 /PRNewswire/ — The National Academy for Drone Sports Excellence (AKSADRON), an initiative under Futurise Sdn Bhd (Futurise), today announced the release of the AKSADRON Impact Report 2025, documenting the progress and achievements of its efforts to develop Malaysia’s drone sports ecosystem between 2022 and 2025.

The report highlights AKSADRON’s role in building a structured national platform for drone sports by combining competitive sports, technical learning and the use of drone sports to strengthen STEM, TVET, innovation and future-ready skills. It also reflects the growing participation of students, educational institutions, government stakeholders, industry partners and drone sports communities in programmes conducted across Malaysia.

The report also outlines AKSADRON’s alignment with the National Drone Sports Strategic Roadmap 2023–2027, or NADSAR, which provides a five-year framework for developing drone sports as both a competitive and recreational activity and as a talent pipeline supporting the broader drone and aerospace industries. This initiative also supports current government priorities, including the Thirteenth Malaysia Plan 2026–2030, National TVET Policy 2030 and Visi Sukan Negara 2030. The roadmap is anchored on three strategic priorities: strengthening the national drone sports landscape, building a collaborative ecosystem and increasing public awareness in drone sports.

Guided by these strategic priorities, AKSADRON’s work has translated into positive and measurable outcomes. From 2022 to 2025, AKSADRON achieved the following:

• Reached more than 10,000 participants through nationwide awareness programmes and activations;
• Trained 2,000 participants, contributing to the development of new drone pilots and emerging athletes;
• Conducted 70 programmes and events, namely, Dronecubator and Drone Hero;
• Organised 7 drone sports tournaments such as Drone Hub Innovation for Future Talent (DRIFT) & Sky Battle;
• Engaged more than 20 stakeholders across government, academia and industry;
• Collaborated with 8 academic and learning institutions and 6 industry stakeholders; and
• Established more than 10 Memorandum of Understanding and Letters of Intent to accelerate collaboration and ecosystem growth.

Shafinaz Salim, Acting Chief Executive Officer of Futurise, said, “The AKSADRON Impact Report 2025 represents an important milestone in our journey to develop a structured and inclusive drone sports ecosystem in Malaysia. The progress achieved since 2022 demonstrates that drone sports are more than a recreational activity. They provide a practical and engaging platform through which young Malaysians can develop technical knowledge, confidence, teamwork, problem-solving abilities and competitive experience”.

Established by Futurise following a mandate from the Malaysian Government in 2022, AKSADRON advances the development of Malaysia’s drone sports ecosystem across four key segments: drone racing, drone soccer, drone e-sports and AI-enabled drone racing.

AKSADRON’s training facility is in Cyberjaya, where it offers public and customised training programmes for individuals, schools, higher-learning institutions and corporate organisations, covering areas such as drone piloting, flight safety, drone handling, technical skills, teamwork and competitive drone sports.

Shafinaz further added, “Through AKSADRON, we are making drone technology more accessible by providing a structured environment where participants can learn, practise and progress. Our Cyberjaya training facility serves as a platform for students, educators, organisations and members of the public to develop practical skills and experience drone sports in a safe and guided setting. We want every training programme to open a pathway, from initial exposure and participation to technical development, competition and future opportunities within Malaysia’s growing drone ecosystem”.

For more details, the AKSADRON Impact Report 2025 will be available soon in Futurise’s website. For those who are keen to explore collaboration opportunities with AKSADRON for trainings and events, may contact [email protected] for more information.

About Futurise

Futurise is a company under the Ministry of Finance. It is mandated by the Government of Malaysia to manage the National Regulatory Sandbox, providing public policy advisory and acting as a key enabler of regulatory solutions to expedite innovation and future-proof Malaysia’s economy.

Follow Futurise & AKSADRON social media for updates:
FB: https://www.facebook.com/futurisemy/
Instagram: https://www.instagram.com/futurisemy ; https://www.instagram.com/aksadron/
TikTok: https://www.tiktok.com/@aksadron
Linkedin: https://www.linkedin.com/company/futurise/ 

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SOURCE Futurise Sdn Bhd

Achieving world-class AI inference performance through Japan-developed 2nm 3D-stacked CPU and server integrated, developed, and manufactured in Japan

KAWASAKI, Japan, Sept. 14, 2026 /PRNewswire/ — Fujitsu Limited today announced that it will begin global sales of its next-generation CPU, FUJITSU-MONAKA^[1], designed and developed in Japan, starting November 2026. This will include sales of the processor as a standalone product to cloud and data center operators and server vendors. Additionally, the company will launch the made-in-Japan Fujitsu MONAKA Server equipped with the FUJITSU-MONAKA CPU, offering high reliability and power efficiency as a sovereign AI infrastructure. Fujitsu MONAKA Server will be made broadly available from November 2026 to data center operators, enterprises, and the academic and HPC sectors in Japan and Europe, contributing to national security.

The FUJITSU-MONAKA CPU integrates Fujitsu’s extensive expertise in processor and server development, achieving world-class computational performance and data supply capabilities with a maximum operating frequency of 3.8GHz and memory transfer speed of 8800MT/s. It delivers twice the AI inference throughput and superior power efficiency compared to other CPUs, effectively halving the number of servers and power consumption required for equivalent processing loads.

Fujitsu MONAKA Server, powered by the FUJITSU-MONAKA CPU, enhances sovereign capabilities through domestic manufacturing, contributing to traceability and supply chain transparency. Furthermore, at a time when power and installation space are significant challenges for AI infrastructure expansion, this CPU server alone can build an AI inference platform. Its space-saving and power-efficient design allows for deployment in air-cooled data centers, significantly increasing customers’ capacity for AI infrastructure expansion. Fujitsu MONAKA Server also supports future scalability through resource pooling technology and reduces cooling energy consumption with Fujitsu’s long-cultivated cooling technologies.

Fujitsu is committed to supporting customers’ autonomy and accountability by providing a sustainable sovereign AI infrastructure with high operability.

For full release click here

Note
[1] FUJITSU-MONAKA: 
This new technology applied to FUJITSU-MONAKA is based on results obtained from a project subsidized by the New Energy and Industrial Technology Development Organization (NEDO).

SOURCE Fujitsu Limited

HONG KONG, Sept. 14, 2026 /PRNewswire/ — Monitoring marine life helps scientists track ecosystem health, improve conservation, and manage fisheries. A promising approach is environmental DNA (eDNA), which refers to trace genetic material naturally released into the water by organisms, such as skin cells, mucus and excreta. By analysing eDNA in water samples, scientists can determine which species are present in a given body of water without the need to physically capture or observe the organisms. This method is of great significance for monitoring marine ecosystems and conserving biodiversity. In practical applications, however, DNA concentrations in seawater are extremely low, making it difficult for traditional membranes to capture it effectively.

A research team from City University of Hong Kong (CityUHK), in collaboration with researchers from several other universities, has successfully developed a novel functionalised membrane that significantly improves the efficiency of collecting and detecting marine organisms’ eDNA, providing a more sensitive and reliable technical tool for monitoring marine biodiversity.

The CityUHK team was led by Professor Kenneth Leung Mei-yee, Vice-President (Research) and Director of the State Key Laboratory of Marine Environmental Health (SKLMEH); and Professor Zeng Zhiyuan from the Department of Materials Science and Engineering and the SKLMEH. The study, titled “A tailored MoS₂ membrane with strong DNA-binding capability enhances aquatic biota detection through environmental DNA metabarcoding“, was published in the leading international journal National Science Review.

The research team coated the surface of a common membrane with an ultra-thin layer of 2D material molybdenum disulphide (MoS₂), enabling the membrane to capture DNA in water more effectively. Experimental results show that this novel membrane significantly improves the detection sensitivity of fish eDNA in both laboratory and field tests.

In controlled experiments, the researchers successfully used the membrane to accurately identify a variety of tropical coral reef fish, including Acanthurus dussumieri, Chrysiptera cyanea, Dascyllus trimaculatus, Microcanthus strigatus, and Paracanthurus hepatus.

For field testing, the research team conducted on-site sampling tests at the Hoi Ha Wan Marine Park. The results showed that the new filter membrane could detect a greater number of fish species, including anchovies, flathead gray mullet and carangid fish, without affecting the overall assessment of the fish community, demonstrating its potential for applications in practical marine monitoring.

“The membrane is simple to prepare and cost-effective, and can be directly integrated into existing water sampling filtration processes. It is expected to find future applications in marine conservation, ecological surveys and long-term environmental monitoring, and is particularly suitable for use in marine areas rich in biological resources but difficult to survey,” noted Professor Leung.

He added that the Ministry of Ecology and Environment is currently promoting the use of eDNA technology in biodiversity surveys, and that the research team’s innovative technology will support and drive the development of this technology.

The corresponding authors of this study include Professor Leung; Professor Zeng; Professor Huang Bolong from the Department of Chemistry at CityUHK; and Professor Qiu Jianwen from the Department of Biology at Hong Kong Baptist University. The findings demonstrate the interdisciplinary integration of advanced materials science and environmental ecology research, creating new avenues for more precise and sensitive marine biological monitoring technologies.

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SOURCE CITY UNIVERSITY OF HONG KONG

New 6U VME SBC Delivers Modern Intel Computing and Graphics, SWaP Optimization and Secure High-Capacity Storage While Preserving Existing Infrastructure and Reducing Modernization Risk

NATIONAL HARBOR, Md., Sept. 14, 2026 /PRNewswire/ — (AFA Air, Space & Cyber Conference, Booth MB400) — Aitech, a global leader in AI-powered rugged embedded computing and connectivity solutions for defense and space applications, today announced the C165 Rugged 6U VME Single Board Computer (SBC), helping defense and aerospace organizations build or modernize mission-critical systems while preserving proven VME infrastructure already deployed across air, land and naval platforms.

As military programs face increasing pressure to improve performance, strengthen cybersecurity and address component obsolescence, many continue to rely on fielded VME architectures that remain operationally effective but cannot easily absorb the cost, schedule disruption and technical risk of a complete platform redesign. The C165 enables program teams to modernize computing capabilities within existing systems, extending platform life and accelerating technology refresh efforts without requiring migration to a new architecture.

Aitech is showcasing the new C165 SBC, along with its mission-ready computing and connectivity solutions that help modernize air, space and defense platforms, at the Air & Space Forces Association Air, Space & Cyber Conference from Sept. 14-16 in National Harbor, Maryland in booth MB400.

“Defense customers need practical modernization solutions that improve mission capability while minimizing program risk,” said Alex Trigoub, product manager, Aitech. “The C165 delivers modern, power-optimized Intel processing, powerful integrated GPU, advanced cybersecurity, versatile I/O and high-capacity secure storage in a rugged 6U VME form factor, allowing customers to enhance performance, address obsolescence challenges and extend the operational life of deployed systems without re-architecting their platforms, while also minimizing upgrade and operational costs.”

The C165 reflects Aitech’s commitment to helping customers modernize and sustain mission-critical systems through a combination of proven technology assets, mission-specific engineering expertise and long-term lifecycle support. As a pin-compatible successor to Aitech’s C164 and C163 SBCs, the C165 provides an efficient upgrade path that helps customers manage technology obsolescence while preserving past investments in qualified hardware, software and platform infrastructure.

Built on the SWaP-optimized 11^th Gen Intel® Core™ i7-1185GRE Tiger Lake UP3 processor with integrated Intel® Iris® Xe graphics, the C165 delivers significantly higher compute and graphics performance than previous-generation VME solutions. It enables system integrators to support increasingly demanding workloads, including mission computing, ISR processing, video analytics and sensor-driven applications, while maintaining compatibility with existing VME deployments.

Beyond performance gains, the C165 addresses the growing cybersecurity and data management requirements of modern defense programs. The board supports up to 32GB of LPDDR4X memory and up to 4TB of secure NVMe storage while incorporating Aitech’s AiSecure™ cybersecurity framework, including TPM 2.0, Secure Boot, Intel Boot Guard, encrypted storage and secure erase capabilities to help protect mission-critical data and system integrity.

Key Features

• 11^th Gen Intel Core i7-1185GRE Tiger Lake UP3 processor
• Intel Iris Xe graphics with 96 execution units
• 2x CPU performance/watt improvement over previous-generation Aitech VME platforms
• More than 2.5x graphics performance improvement
• Up to 32GB LPDDR4X-4267 memory with in-band ECC for optimization of memory-intensive workloads
• Up to 4TB  self-encrypted NVMe SSD  with Quick Erase and Secure Erase
• AiSecure cybersecurity framework with TPM 2.0, Secure Boot and Intel Boot Guard support
• Support for PMC and XMC mezzanine sites for functional and I/O extensions
• Pin-compatible upgrade path for Aitech C164 and C163 deployments
• Air-cooled and conduction-cooled variants
• Rugged 6U VME form factor for defense and aerospace systems

Availability and Technical Details
The C165 is now available for mission development and platform modernization programs.
For more information, visit Aitech’s website.   

About Aitech
Aitech Rugged Group, Inc. (“Aitech”) develops and delivers mission-critical electronics that equip defense and space organizations with faster insights, greater reliability, and the technology advantage needed to succeed in every domain. As the world’s first independent provider of open-systems COTS and MOTS embedded computing solutions, Aitech combines proven computing building blocks, application-specific engineering, and long-term lifecycle support to solve complex hardware challenges.

With a portfolio of SOSA-aligned single-board computers, AI-enabled GPGPUs, rugged networking solutions, and integrated mission computing platforms, Aitech helps accelerate defense modernization while reducing program risk and complexity. For more than 40 years, Aitech has delivered mission-proven solutions across sea, land, air, and space domains. Customers include Airbus, BAE Systems, Boeing, Hindustan Aeronautics Limited (HAL), Israel Aerospace Industries (IAI), Larsen & Toubro Limited (L&T), Leonardo, Lockheed Martin, NASA, Northrop Grumman, Rafael, and Virgin Galactic.

Aitech is built for your mission. For more information, visit www.aitechsystems.com.

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SOURCE Aitech

STOCKHOLM, Sept. 14, 2026 /PRNewswire/ — During the period September 7 – September 11, 2026, Telefonaktiebolaget LM Ericsson(publ) (“Ericsson“) (LEI code 549300W9JLPW15XIFM52) repurchased own Class B shares (ISIN: SE0000108656) as follows:

The share repurchases are a part of the share buyback program of up to SEK 15,000,000,000 which Ericsson announced on April 16, 2026, and which runs between April 23, 2026, and March 31, 2027, at the latest. The Board of Directors intends to propose to the 2027 Annual General Meeting that the repurchased shares, other than those used to fulfil Ericsson’s obligations under its share-related incentive programs, are cancelled.

The share buyback program is executed in accordance with the Regulation (EU) No 596/2014 of the European Parliament and of the Council on market abuse (MAR) and the Commission Delegated Regulation (EU) 2016/1052 of 8 March 2016 supplementing MAR (the Safe Harbour Regulation).

All acquisitions have been carried out on Nasdaq Stockholm by Goldman Sachs Bank Europe SE on behalf of Ericsson. A full breakdown of the transactions is attached to this announcement.

Following the repurchases above, Ericsson’s holding of treasury stock amounts to 107,518,663 Class B shares. There are in total 3,371,351,735 shares in Ericsson, 261,755,983 shares of Class A and 3,109,595,752 shares of Class B.

NOTES TO EDITORS:

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ABOUT ERICSSON:
Ericsson’s high-performing, programmable networks provide connectivity for billions of people every day. For 150 years, we’ve been pioneers in creating technology for communication. We offer mobile communication and connectivity solutions for service providers and enterprises. Together with our customers and partners, we make the digital world of tomorrow a reality. www.ericsson.com

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SOURCE Ericsson

YANTAI, China, Sept. 14, 2026 /PRNewswire/ — Sungrow, a global leading renewable energy company, recently hosted the latest edition of its PhD Talk series in China’s Bohai Bay, bringing together experts and industry representatives in offshore PV, island microgrids, deep-water offshore wind and marine conservation.

Under the theme “The Power of Bridge: Bridge to The Deep Blue,” the event identified five key trends shaping offshore renewables in the move from demonstration projects toward commercial deployment.

Offshore systems must withstand salt spray, high humidity, waves, tides and typhoons while navigating limited operation and maintenance (O&M) windows, insufficient grid support and coordination across multiple types of equipment.

Trend 1: Scenario-Defined Design Replaces a One-Size-Fits-All Approach

Offshore equipment cannot simply replicate land-based products, and different marine environments demand different designs. David Sun, General Manager of the R&D Center at Sungrow’s Utility PV Business Unit, noted that tropical waters bring heat and humidity, cold-water environments create condensation risks, and nearshore industrial zones expose equipment to chemical corrosion.

Sungrow therefore uses a unified, high-standard technology platform while adapting materials, sealing processes and thermal management strategies to local conditions.

Trend 2: AI-Powered Reliability Supports Offshore Solar’s Move to Commercial Scale

As offshore PV moves from demonstration projects toward commercial operation, harsher environmental loads and mounting cost pressures remain key challenges, according to Hui Xing, Chief Engineer of POWERCHINA Northwest Engineering Corporation Limited’s New Energy Engineering Institute.

David further emphasized that project economics extend beyond upfront equipment costs to downtime, offshore inspections and long-term maintenance. Sungrow’s Smart IV Curve Diagnosis identifies string faults, while self-learning algorithms monitor inverter air-duct health, enabling early warnings and dust removal. MPPT-level insulation detection reduces fault-location time to one-sixth of that required by conventional inverter-level diagnosis, while AI-based fault localization pinpoints issues to individual modules within a string.

Trend 3: Lifecycle Reliability and Proactive Safety Become Core Design Requirements

The SG465HX utility string inverter incorporates IP66 protection, C5-H corrosion resistance, a fully sealed electronics chamber, an IP68-rated fan, weather-resistant sealing materials and intelligent active dehumidification.

In a 1,440-hour cyclic neutral salt spray test (two hours in 5% sodium chloride spray and 22 hours at 40±2°C and 93% relative humidity per cycle), no corrosion appeared on the enclosure, structural parts or core internal components. Sungrow also received a third-party C5-H certification report.

The inverter’s proactive safety features include intelligent string shutdown, AC and DC terminal temperature monitoring, a DC switch with a trip mechanism, and 24-hour insulation monitoring. Sungrow also developed two-stage waterproof terminal caps for protection during transportation, construction and long-term operation, including IP68-rated PA66 caps for unused terminals. A dedicated offshore DC switch uses corrosion- and wear-resistant coatings to reduce the risk of contact sticking and failure to interrupt fault current caused by salt spray.

Trend 4: Grid-Forming Technology Becomes the Backbone of Island Microgrid Stability

Island microgrids face three core challenges: generation uncertainty, load uncertainty and the absence of external grid support, making grid-forming technology and coordinated power-system control essential to stable power supply, according to Dr. Liu Hangyue, Deputy General Manager of Sungrow’s Microgrid and Grid Solutions Center.

David said Sungrow’s inverter portfolio offers grid-forming capability under all grid conditions, letting PV inverters in microgrids establish voltage and support frequency through grid-forming algorithms. In PowerMatrix, each sub-array can operate independently in grid-forming mode, enabling 10-millisecond voltage stabilization and a 5-millisecond inertia response.

Future island energy systems will require coordinated control across solar, wind, storage, the grid and loads, rather than relying on individual devices alone.

Trend 5: Deep-Water Offshore Wind Shifts from Equipment Adaptation to System-Level Co-Design

As offshore wind expands into deeper waters and farther from shore, the challenge is shifting from individual-device reliability to system-wide coordination and value-chain collaboration. Larger turbines can reduce costs and improve efficiency but introduce new issues involving fluid-structure interaction, material properties and multidisciplinary coordination, according to Xu Guodong, Deputy Chief Engineer of Windey Energy Technology Group.

Addressing this shift, Dr. Wang Lingxiang, Vice President of Sungrow and President of its Wind Energy Business Unit, said deep-water sites, evolving power-system requirements and complex marine conditions place greater demands on the reliability, overload capability and intelligent O&M of wind converters.

Electrical equipment must move from passive adaptation to active integration through system-level co-design with generators, cables and transformers, as well as participation in turbine load control and intelligent shutdown strategies. Grid-forming applications must also reflect specific grid-connection and power-transmission configurations, strengthening grid support while safeguarding generators and managing turbine loads. Hardware upgrades should be based on system design requirements.

Beyond technology, Sungrow Foundation joined WWF and the One Planet Foundation to launch a marine “Sun Forest” ecological restoration initiative in Bohai Bay, aiming to restore seagrass and macroalgal beds to improve marine habitats. The foundation also donated a 10.35 kW/10 kWh solar-plus-storage system, expected to generate approximately 12,000 kWh annually, to support emergency and stable power supply for an island community.

This edition of Sungrow’s PhD Talk series traced the industry’s shift from a focus on individual equipment performance toward scenario-specific design, lifecycle reliability, intelligent O&M and system-wide coordination. To support this transition, Sungrow will continue exploring solutions for different marine environments and energy applications through innovation in power conversion and grid technologies.

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SOURCE Sungrow

CHENGDU, China, Sept. 14, 2026 /PRNewswire/ — Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (“Kelun-Biotech” or “the Company”, 6990.HK) announced that results from the phase III registrational study of its novel human epidermal growth factor receptor 2 (HER2)-targeted antibody–drug conjugate (ADC) trastuzumab botidotin (舒泰莱^®) in HER2-positive unresectable or metastatic breast cancer (BC) have been published in Journal of Clinical Oncology (JCO, impact factor (IF)=44.7). Professor Xichun Hu and Professor Hongxia Wang of Fudan University Shanghai Cancer Center, and Dr. Junyou Ge, Director of the National Engineering Research Center of Targeted Biologics act as the co-senior authors. Professor Jian Zhang of Fudan University Shanghai Cancer Center, Professor Quchang Ouyang of Hunan Cancer Hospital, Professor Qingyuan Zhang of Harbin Medical University Cancer Hospital, Professor Huihui Li of Cancer Hospital of Shandong First Medical University, and Professor Xu Wang of Tianjin Medical University Cancer Institute and Hospital act as the co-first authors. These findings had previously been selected as a Late-Breaking Abstract (LBA) and presented as an oral presentation at the 2025 European Society for Medical Oncology (ESMO) Congress.

This randomized, open-label, multicenter phase III study was designed to evaluate the efficacy and safety of trastuzumab botidotin monotherapy versus trastuzumab emtansine (T-DM1) in patients with HER2-positive unresectable or metastatic BC who had received prior trastuzumab and taxane-containing regimens. A total of 365 patients were randomized 1:1 to receive trastuzumab botidotin or T-DM1. The primary endpoint was progression-free survival (PFS) assessed by blinded independent central review (BICR), and secondary endpoints included overall survival (OS), objective response rate (ORR), and duration of response (DoR).

As of the data cutoff date of April 26, 2025, with a median follow-up of 14.9 months, efficacy results showed:

• Median PFS was significantly prolonged in the trastuzumab botidotin group compared with the T-DM1 group (11.1 months vs. 4.4 months; hazard ratio (HR) = 0.39) (Figure A), meeting the primary endpoint of the study; consistent PFS benefit was observed across all prespecified subgroups (Figure B).
   
•  Trastuzumab botidotin group demonstrated deeper and more durable tumor responses compared with T-DM1 group, with an ORR of 76.9% vs. 53.0% and a median DoR of 12.2 months vs. 5.7 months (Figure C).
•  OS data were not mature in both groups, but an OS benefit trend was observed in trastuzumab botidotin group, demonstrating a 38% reduction in the risk of death (Figure D).

In terms of safety, patients in the trastuzumab botidotin group had a low incidence of interstitial lung disease (ILD), and the incidences of hematologic, hepatic, and gastrointestinal toxicities were notably lower than those in the T-DM1 group, along with lower rates of serious adverse events (SAEs) and treatment discontinuations. The most common treatment-related adverse events (TRAEs) in trastuzumab botidotin group were ocular events, which could be recovered or reversed after management with standardized strategies.

The publication of the phase III results for trastuzumab botidotin in Journal of Clinical Oncology marks a major international academic breakthrough for a domestically developed HER2 ADC backed by high-level clinical evidence. This is the first phase III trial in China for a HER2 ADC compared head-to-head with T-DM1 with positive results. The data showed that trastuzumab botidotin demonstrated improvements in key efficacy endpoints including PFS, ORR, and DoR, along with a favorable safety profile. Based on these positive results, trastuzumab botidotin has been approved by China’s National Medical Products Administration (NMPA) for the treatment of second-line or later HER2-positive BC, becoming the first domestically developed HER2 ADC approved for this indication in China and providing a new treatment option for patients with HER2-positive advanced breast cancer.

About Trastuzumab botidotin(舒泰莱^®)

Trastuzumab botidotin is a differentiated HER2 ADC to treat advanced HER2+ solid tumors. As an innovative HER2 ADC developed by the Company, it conjugates a novel, monomethyl auristatin F (MMAF) derivative (a highly cytotoxic tubulin inhibitor, Duo-5) via a stable, enzyme-cleavable linker to a HER2 monoclonal antibody with a DAR of 2. Trastuzumab botidotin specifically binds to HER2 on the surface of tumor cells and is internalized by tumor cells, releasing the toxin molecule Duo-5 inside the cell. Duo-5 induces tumor cell cycle arrest in the G2/M phase, leading to tumor cell apoptosis. After targeting HER2, trastuzumab botidotin can also inhibit the HER2 signaling pathway; it has antibody-dependent cell-mediated cytotoxicity (ADCC) activity.

Based on the results of a multi-center, randomized, open-label, controlled Phase 3 KL166-III-06 study, trastuzumab botidotin was approved for marketing by the NMPA for adult patients with unresectable or metastatic HER2 positive BC who have received one or more prior anti-HER2 therapy. At a pre-specified interim analysis, trastuzumab botidotin monotherapy demonstrated a statistically significant and clinically meaningful improvement in the primary endpoint of PFS as assessed by the BICR compared with T-DM1; the beneficial trend for OS of trastuzumab botidotin was also observed.

Currently, the Company has initiated an open, multi-center Phase 2 clinical study of trastuzumab botidotin in the treatment of HER2+ unresectable or metastatic BC that previously received a topoisomerase inhibitor payload ADC.

About Kelun-Biotech

Kelun-Biotech (6990.HK) is a holding subsidiary of Kelun Pharmaceutical, which focuses on the R&D, manufacturing, commercialization and global collaboration of innovative biological drugs and small molecule drugs. Kelun-Biotech focuses on major disease areas such as solid tumors, autoimmune, inflammatory, and metabolic diseases, and in establishing a globalized drug development and industrialization platform to address the unmet medical needs in China and the rest of world. Kelun-Biotech is committed to becoming a leading global enterprise in the field of innovative drugs. At present, Kelun-Biotech has more than 30 ongoing key innovative drug projects, of which 4 projects with 8 indications have been approved for marketing, 2 projects with 3 indications are in the NDA stage and more than 10 projects are in the clinical stage. Kelun-Biotech has established one of the world’s leading proprietary ADC and novel DC platforms, OptiDC™, and has 2 ADC projects with 5 indications approved for marketing, and multiple ADC and novel DC assets in clinical or preclinical research stage. For more information, please visit https://en.kelun-biotech.com/. 

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SOURCE Kelun-Biotech

XIAMEN, China, Sept. 14, 2026 /PRNewswire/ — Curated by the Italian Trade Agency (ITA) in collaboration with Ministry of Foreign Affairs and International Cooperation (MAECI) and jointly with the Ministry of Enterprises and Made in Italy (MIMIT), the Italy National Pavilion officially opened at 12:00 on September 8 during the 26th China International Fair for Investment and Trade (CIFIT) in Xiamen. Official representatives from China and Italy attended the opening ribbon-cutting ceremony. Under the theme “Italy: A Land of Opportunities”, Italy showcased its investment value and cooperation potential to the Chinese market at this edition of CIFIT.

As the world’s eighth-largest economy and the EU’s second-biggest manufacturing nation, Italy offers mature FDI support policies and robust industrial bases. At CIFIT, multiple Italian authorities showcased Italy as a key European investment hub for Chinese firms, introducing full-cycle one-stop government services, local investment rules, incentives, business climate and premium opportunities.

Focusing on automotive, aerospace, green supply chains, circular economy and life sciences, the booth presented free-trade zone industrial policies and incentives, alongside a curated list of high-quality Italian real estate projects. Investment guides covering procedures, project proposals and benefits were available on site.

Throughout CIFIT, the professional investment teams composed of senior officers from the Technical Secretariat of the Committee for the Attraction of Foreign Investment (STCAIE) and the Special Unit for Attracting and Unblocking Investments (UMASI) under the Ministry of Enterprises and Made in Italy, China-based representatives of the Invest in Italy initiative (including the FDI Desk Beijing and FDI Desk Hong Kong of ITA), as well as expert teams from Invitalia, held multiple B2B meetings with interested Chinese enterprises, providing face-to-face one-stop investment advisory services.

A series of seminars were hosted within the pavilion. Among them, the special seminar titled “ITALIAN FDI ATTRACTION POLICIES AND OPPORTUNITIES“ held on the afternoon of September 8 drew more than 200 audiences. Italian speakers shared insights on full-cycle supporting services for foreign investors in Italy and offered an in-depth interpretation of Italy’s foreign direct investment support system.

Amedeo Teti, Director-General of STCAIE of MIMIT, gave a comprehensive overview of Italy’s new framework for attracting foreign investment. Augusto Reggiani, Director of Italian Foreign Investments Attraction Unit – INVESTMENT SCREENING EXPERT GROUP in MIMIT, elaborated on tailored investment opening measures for investors. Giovanni Savini, Director of UMASI of MIMIT, outlined the unit’s role in facilitating the implementation of major investment projects of national strategic significance. A Q&A session followed the seminar, enabling in-depth exchanges between participating enterprises and speakers.

Besides the flagship seminar, on September 9 two smaller investment promotion sessions were co-hosted by Invitalia and ITA’s investment promotion division. The sessions covered foreign investment opportunities in automotive, aerospace, green supply chains, life sciences and circular economy, and illustrated Italy’s unique competitive advantages as an EU manufacturing base.

Cultural experience activities will also be arranged at the pavilion, featuring tastings of Italian fine wine and Padano cheese. Italian coffee and Made in Italy ice cream will be served throughout the days, vividly presenting Italian lifestyle.

According to relevant officials of ITA, the participation achieved fruitful results. CIFIT served as an efficient platform where Chinese enterprises interested in investing in Italy obtained first-hand advice directly from Italian investment specialists, further strengthening their intention to invest in Italy. Italy attaches great importance to economic and trade ties with China and warmly welcomes Chinese enterprises to invest in Italy. After the fair, ITA China-based offices and FDI Desk Beijing and FDI Desk Hong Kong of ITA will continue to provide investment advisory services for market entities considering Italy.

View original content to download multimedia:https://www.prnewswire.com/apac/news-releases/italy-national-pavilion-shines-at-the-26th-china-international-fair-for-investment-and-trade-302877298.html

SOURCE Italian Trade Agency (ITA)